Cognitive impairment in euthymic major depressive disorder: A meta-analysis

E Bora; BJ Harrison; M Yücel; C Pantelis

Journal article

Cognitive impairment in euthymic major depressive disorder: A meta-analysis

E Bora, BJ Harrison, M Yücel, C Pantelis

Psychological Medicine | Published : 2013

DOI: 10.1017/S0033291712002085

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Abstract

Background There is evidence to suggest that cognitive deficits might persist beyond the acute stages of illness in major depressive disorder (MDD). However, the findings are somewhat inconsistent across the individual studies conducted to date. Our aim was to conduct a systematic review and meta-analysis of existing studies that have examined cognition in euthymic MDD patients. Method Following a systematic search across several publication databases, meta-analyses were conducted for 27 empirical studies that compared euthymic adult MDD patients (895 participants) and healthy controls (997 participants) across a range of cognitive domains. The influence of demographic variables and confound..

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University of Melbourne Researchers

Ben Harrison Author

Christos Pantelis Author

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Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

B.J.H. was supported by a National Health and Medical Research Council of Australia (NHMRC) Clinical Career Development Award (no. 628509). M.Y. was supported by an NHMRC Senior Research Fellowship (no. 1021973). C. P. was supported by a NHMRC Senior Principal Research Fellowship (no. 628386), a NARSAD Distinguished Investigator Award from the Brain and Behavior Research Foundation and a NHMRC Program Grant (no. 566529).